DOI: 10.36347/sajp.2020.v09i08.002

Pages: 239-243

The contagious disease COVID-19 is a recently out-broken pandemic situation which threatens human kind all over the world. While considering the mortality and severity of this disease, the author attempted to identify the possible inhibition of RNA-dependent RNA polymerase (RdRP) or RNA replicase which catalyzes the replication of RNA from an RNA template by certain bioactive components. So certain herbs which are used as febrifuges in Siddha medicine were analyzed through molecular docking studies. The compounds Betulinicacid, Amaranthin, Betacyanin, Cadambine, 14 –deoxy Androgapholide, lupeol, Neoandrographolide, Tubulosin and Isovitexin have binding energy comparable to Remdesivir.