DOI: 10.36347/sajb.2016.v04i12.012

Pages: 1128-1131

Extensive intraductal component positive carcinoma (EICPC) of breast is a well defined entity. Nevertheless few data exist concerning their characteristics and prognostic behaviour. Our objective was to describe clinicopathological and prognostic features of EICPC. This is a retrospective single centre study. All the 26 patients with a histopathological diagnosis of EICPC listed in our institutional data base during the period of 2013 to 2016 were included in this study. Age of patients ranged from 30 to 67 years with median age of 48 years and 15 patients (58%) were postmenopausal. Most of the cases (69%) were negative for hormone receptor expression (ER, PR) and positive for HER2 (85%). Regarding pathological staging most of the cases were pT1a (58%) and pNo(77%). Invasive component was 10% or less of the total area of tumor in 19 cases (73%). Maximum size of invasive component was 1cm or less for 20 (77%) cases. Surgical margins were free in 24 cases (92%). Mean duration of follow up was 21months and with exception of 1 case, for which we lost follow up, all other cases are under regular follow up and are doing well.