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Scholars Academic Journal of Pharmacy | Volume-9 | Issue-11
New UV Spectrophotometric Method for the Estimation of Atazanavir Sulfate in Bulk and Pharmaceutical Dosage Form
Soundarya K, Hemant Kumar T, Manjunath SY
Published: Nov. 6, 2020 |
277
170
DOI: 10.36347/sajp.2020.v09i11.002
Pages: 296-300
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Abstract
A simple, fast and reliable UV spectrophotometric method has been developed for estimation of atazanavir sulphate in bulk and pharmaceutical dosage form. Estimation was carried out at λmax 249 nm using 0.1 N HCl as solvent. The linearity was observed in the range of 10-90 μg /ml with correlation coefficient (r) 0.999. The percentage recovery was found to be in range of 99.84-100.18%. The proposed method was found to be simple, accurate, precise, and reproducible and gave the acceptable recovery of the analyte which could be directly and easily applied to analysis of bulk and pharmaceutical tablet dosage form of atazanavir sulphate.