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Scholars Academic Journal of Biosciences | Volume-5 | Issue-12
Anti-Dermatophyte Activity of Hedychium spicatum Oil and Its Topical Formulation-Cream
Kavita Salkar, Chetna Chotalia, Sachin Kundalwal, Rajiv Salvi
Published: Dec. 30, 2017 |
260
165
DOI: 10.36347/sajb.2017.v05i12.009
Pages: 877-880
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Abstract
A skin infection due to Dermatophytes is the most prevalent skin disorder even in the todays world. Plant based products are being looked upon as an alternative to synthetic drug treatments due to the various side-effects reported for the later. Hedychium spicatum oil was tested for its Anti-dermatophyte potential and MIC in the range of 30 to 40 mcg/ml was obtained for it. Further a 5% cream developed using this oil also showed a potent activity of 0.5 mg/ml (MIC) against the dermatophyte species. The new Anti-dermatophyte formulation can be considered as an alternative option for fungal skin infections.