DOI: 10.36347/sjams.2017.v05i07.002

Pages: 2491-2495

Hyper immunoglobulin E Syndrome (Hyper-IgE Syndrome/ HIES) more commonly referred to as Job’s Syndrome was first explained in 1966 by Davis SD on the basis of characteristic eosinophilia, eczema and recurring skin and pulmonary infections in two female subjects. We present the case report of a 5 Year old child with recurrent fever, cough and skin problems who presented with fever, cough and swelling of right eyelid. Patient has past history of recurrent swellings on different parts of body along with fever, 3 episodes of chest infection and 1 episode of mastoiditis. Patient also features recurrent episodes of localize itching at different parts of body since the age of 15 months. On examination, Child was febrile, anemic and discrete firm and mobile enlargement of cervical lymph node was noted. There was subcostal and intercostalrecessions, harsh vesicular breathing with coarse crepitations bilaterally. Painful swelling of the right eye was erythematous and tender to touch, blepharitis with multiple stye was noted, and patient had prominent forehead, hypertelorism and broad nose. Labs revealed absolute eosinophil count enormously raised and significant increase in IgE levels has been noticed. Finding consistent with diagnosis of Aspergilloma was found on CT scan chest. Above mentioned clinical and laboratory findings were put in scoring system and diagnosis of job syndrome was made.