DOI: 10.36347/sjams.2017.v05i07.017

Pages: 2573-2580

Study the effect of low pressure, oxygen therapy (TPOT), and negative pressure wound therapy and the combination of both as three adjuvant therapies were analyzed to assess the rate of healing of diabetic foot wound. Our study was done on 20 patients with difference diabetic foot ulcer sizes. Our results revealed a higher rate of healing when using alternating combined VAC and TPOT in either good perfuse limb or in a poor perfuse limb as indicated with ABPI, in addition; the total duration for complete healing showed high significant shortening when using this combined therapy. Success in wound care may be improved by a personalized wound care therapy. The key lies in our ability to raise the normoxia set point of the wound by transient TPOT that allows the VAC angiogenesis hypoxic response to act with adequate wound oxygenation that maintain the viability of the deep pockets and allows tissue repair.