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Scholars Journal of Applied Medical Sciences | Volume-8 | Issue-01
Microbiological Pattern in Acute Exacerbation of COPD- A Retrospective Study at MIMS, Mandya
Chethan Kumar K L, Shivakumar K M
Published: Jan. 14, 2020 | 159 123
DOI: 10.36347/sjams.2020.v08i01.018
Pages: 89-91
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Abstract
Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic disease which is characterized by persistent respiratory symptoms and airflow limitation that is not fully reversible. COPD is a major cause of morbidity and mortality throughout world including in India. Major reason for hospital admissions in these patients is exacerbation. An exacerbation of COPD is an acute event characterized by a worsening of the patient’s respiratory symptoms that is beyond normal day-to-day variations. Bacterial infections are the most common cause of acute exacerbation of COPD. Objective: To identify the common bacterial pathogens responsible in patients admitted with acute exacerbation of COPD to our hospital. Material and Methods: This is a retrospective study done at Department of General Medicine, MIMS, Mandya among patients admitted with acute exacerbation of COPD. 60 patients admitted with acute exacerbation are included in this study. Sputum culture reports obtained from case sheets, data entered into MS Excel sheet and analysed. Results: 60 patients were included in the study, of the 60 patients microbial isolates were seen in 43.3% (26) cases. Among positive culture, Streptococcus pneumonia is the most common pathogen isolated in 38.46% cases followed by pseudomonas aeuroginosa (23.07%), klebsiella pneumonia (15.38%), staphylococcus aureus (7.6%), H. influenza (3.84%), E. coli (3.84%), and Acinetobacter (3.84%). Sputum AFB was positive in 3.84% (1 patient).