DOI: 10.36347/sjams.2017.v05i07.064

Pages: 2845-2850

Arterial stiffness and type 2 diabetes Mellitus (T2DM) are associated with increased risk for cardiovascular disease (CVD) and mortality. By assessing the arterial stiffness in diabetics, the risk of CVD could be quantified in T2DM. Aim of this cross sectional study to assess the association of arterial stiffness and T2DM. 25 normal and 60 atleast 1year history of T2DM males, aged 25 to 65 years of western Rajasthan were examined for arterial stiffness. Anthropometric data such as weight and height were taken to derive Body Mass Index (BMI). Right and left brachial ankle Pulse Wave Velocities (Br Ank PWV) and carotid to femoral Pulse Wave Velocity (cf PWV) were taken as indices of regional and central arterial stiffness respectively. On other hand right and left, brachial and ankle Arterial Stiffness Indexes (ASI) are taken as indices for corresponding local arterial stiffness. These were measured by an automated device Periscope (developed by genesis medical system, Hyderabad) based on oscillometric technique. Results were compared by Student‘t’ Test by Data Analysis ToolPak in Microsoft Excel, considering p value <0.05 as significant. PWVs (in cm/sec) were elevated in T2DM as compare to Normal Control significantly (p<0.01) as Rt Br Ank PWV (1821.25±646.23 vs 1358.31±246.30), Lt Br Ank PWV (1479.72±277.55 vs 1001.94±260.67), cf PWV (1136.10±348.54 vs 750.08±191.36) but difference between all recorded ASI were not significant statistically (p>0.05). Our study concluded that central arterial stiffness, but not local peripheral arterial stiffness, were significantly associated with atleast 1 Year old T2DM in young to early aged overweight to obese male population of western Rajasthan.