DOI: 10.36347/sjams.2018.v06i01.013

Pages: 64-68

Urinary Tract Infections (UTI) are the common infections after the respiratory tract infections. The present study was designed to isolates the bacterial uropathogens and their antibiotic susceptibility pattern in outpatients and inpatients of our tertiary care and to determine an empirical treatment pattern for patients with UTI. A total of 500 urine samples were obtained with a clinical diagnosis of UTI. The samples were cultured and antibiotic susceptibility of isolates determined by disc diffusion method. Of 500 urine samples processed (310 from inpatients and 190 from outpatients), 176(35.20%) yielded bacterial isolates. About 136(43.87%) samples from inpatients and 40 (21.05%) from outpatients showed significant bacteriuria. Escherichia coli predominated organism isolated in both groups, followed by Klebsiella spp. and Pseudomonas spp., Acinetobacter spp., and Enterobacter spp., which were isolated from only the inpatient urine samples. Sensitivity to Nitrofurantoin varied from 65% to 90% and fluoroquinolone resistance was documented as 25%-50%. Resistance to amikacin, ceftazidime, and ceftriaxone was less than 25%. Imipenem was found no resistance of the bacterial isolates. E. coli and Klebsiella spp. are the major bacteria uropathogens. Resistant strains are prevalent in the community, as evident by the fact that there is not much difference in resistance patterns of isolates from inpatients and outpatients. Taking into account the resistant pattern, Nitrofurantoin represents the option of first choice for empirical therapy of uncomplicated UTI.