DOI: 10.36347/sjams.2018.v06i01.032

Pages: 145-147

This study was carried out between February and April 2017. This study aimed to evaluate serum lipid profile (Total cholesterol (T CHOL), triglycerides (TG), high density lipoprotein (HDL) and low density lipoprotein (HDL)) in atopic dermatitis (AD) patients. Atopic eczema is a very common skin condition. It may start at any age but the onset is often in childhood. It may also start later in life in people who did not have Atopic eczema as a child. Blood samples were collected into plain containers from each participant (40 patients and 40 healthy individuals as control). Serum lipids were measured with semi-automated analyzer Spec BTS 350 using enzymatic methods. Data were analyzed using SPSS version 16 and presented as mean ± SD. P value < 0.05 was considered significant. The means of T CHOL in the patients and control group were (145 mg/dl ±47) and (162 mg/dl ±12) respectively. The means of TG in the patients and control group were (100 mg/dl ± 60) and (115 mg/d ±22) respectively. The means of HDL in the patients and control group were (31 mg/dl ±7) and (70 mg/dl ±5) respectively. The means of LDL in the patients and control group were (93 mg/dl ±38) and (69 mg/dl ±11) respectively. Results of the patients when compared to that of the controls, showed a significant decrease in CHOL (P = 0.02) and HDL (P = 0.00), a significant increase in LDL (P = 0.00) and no significant difference in TG (P = 0.15). Sera of Sudanese patients with atopic dermatitis showed a significant higher level of LDL, lower level of HDL and total cholesterol and no change in triglyceride level when compared with non-atopic dermatitis controls.