DOI: 10.36347/sjams.2018.v06i01.040

Pages: 185-187

Type 2 diabetes mellitus is assumed to be associated with disturbances in the plasma level of several trace elements. There is accumulating evidence that the metabolism of several trace elements is altered in patients with type 2 DM and that these nutrients might have specific roles in the pathogenesis and progression of this disorders. The aim of the present study is to estimate the levels of essential trace elements including copper (Cu), chromium (Cr) in type 2 diabetic patients and healthy control. Thirty three patients with type 2 DM and thirty three healthy control. Blood samples of all individuals were collected after an overnight fasting for estimation of blood glucose, copper, chromium. Fasting blood glucose (FBG) was estimated using enzymatic spectrophotometric method while trace elements concentration were measured with Atomic Absorption Spectrophotometer. chromium in the patients and control group were ( mg/L ± ) and ( mg/ L ± ) respectively copper in the patients and control group were ( mg/ L ± ) and ( mg/ L ±12) respectively. Results of the patients when compared to that of the controls, showed a significant decrease in chromium (P = 0. 000) and copper (P = 0.000). The study concluded that a decrease of chromium and copper is associated with diabetes mellitus.