DOI: 10.36347/sjams.2018.v06i01.077

Pages: 382-386

Menopause also known as the climacteric is although not a disease, is associated with annoying physiological changes, and varied symptoms such as hot flushes, night sweat, urinary and genital changes, dyspareunia, insomnia, and many psychological dysfunction such as anxiety, depression lack of concentration, and decreased self-esteem. Menopause in women is a physiologic process that occurs around 45-55 years. Elevation in uric acid and deranged lipid profile are associated with increased stroke risk. Correlation of lipid profile and serum uric acid level in postmenopausal women. Fifty healthy postmenopausal women were included in study, five ml. of venous blood was taken in red vacutainer and serum was separated. Lipid profile and Uric acid was estimated by enzymatic method in auto analyser. Exclusion Criterion washistory of cardiovascular diseases, history of rheumatoid arthritis, history of radiotherapy, history of liver and renal disease, history of endocrinal disease, women those on antioxidant and vitamin supplements and postmenopausal women on HRT. It was found that uric acid has positive correlation with TG, VLDL, and total cholesterol while having negative correlation with HDL Decreased HDL level and increased other lipid profile parameters e.g. TG, Cholesterol, VLDL, LDL in postmenopausal women, and increased serum uric acid level in postmenopausal women than premenopausal women. Postmenopausal women are more prone for gout and cardiovascular disease.