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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-01
Seroprevalence of Dengue cases detected by ELISA technique in Bharatpur District of Rajasthan
Avinash Pande, Neeraj Kumar, Sunita Pande, Renuka Chauhan, Mukesh Kumar Khorwal
Published: Jan. 30, 2018 | 139 146
DOI: 10.36347/sjams.2018.v06i01.084
Pages: 433-438
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Abstract
Dengue is a common febrile arthropod borne viral disease caused by any of the four serotypes of dengue virus. It has wide spectrum of clinical presentation and often has unpredictable clinical evolution and outcome. Approximately 50 million infections occur annually world-wide. An increase in the number of cases of dengue has been noticed in India during recent years. Present study was carried out to determine seropositivity, clinical profile and seasonal variation of dengue infection in Bharatpur district of Rajasthan, India. Study was carried out from suspected dengue patients attending Government RBM hospital during the period January to December 2017. Blood samples were collected from 1167 patients with dengue like illness and serum separated. All samples were tested for both Dengue NS1 antigen & IgM antibody ELISA. Prevalence of dengue NS1 Ag ELISA 157/717 (21.90%) samples were positive and for dengue IgM Ab ELISA 81/450 (18.00%) samples were positive. The total prevalence of dengue was 238/1167 (20.40%) in the district. Total number of positive case (NS1 antigen and IgM antibody ELISA inclusive) shows that maximum patient were in 1 to 30 year age group. Males were more affected (22.90%) than females (15.95%). The highest numbers of samples were collected during rainy season that is from September to November and highest positivity of dengue virus had been reported during this period. Number of dengue cases in Bharatpur district showed a gradual increase from August to October. The disease started spreading in August, peaked in October and slowly tapered by December.