DOI: 10.36347/sjams.2017.v05i08.044

Pages: 3198-3203

Preeclampsia complicates approximately 5% of all pregnancies. Pre-eclampsia affects the kidney both functionally and morphologically. Diastolic flow is directly related to peripheral vascular resistance. PIH causes significant down stream resistance changes in renal artery. It has been established that continuous vasospasm of proximal renal artery is implicated in the pathogenesis of PIH, while in normotensive patient increase in total circulating blood volume, and thus mildly reduced blood pressure. The objective is to evaluate renal sono morphological and renal Doppler changes (RI and PI) in PIH and normal pregnant patients. It is prospective study, non-randomized done in 15 months, taking 50 normotensive pregnant subjects and 50 PIH subjects with exclusive criteria of Patients with pre-existing renal disease, pre-existing HT, Diabetes mellitus and patients having active UTI. The PSV, EDV and acceleration time of right main renal artery were significantly higher in subjects with PIH. Resistive index was higher in patients with PIH. Based on the mean values of renal artery Resistivity, Pulsatility index and Accleration time ,a cut off value of 0.7 for RI,1.2 for PI and AT>100 milisec were taken to differentiate normal and abnormal values. Renal volume was increased in PIH subjects of our study groups. Our study suggests significant difference in the renal size and Doppler waveform in Normotensive pregnancy and in pregnant women with PIH.PI, AT and RI correlate very well with peripheral vascular resistance.