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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-08
Successful Slow Induction of Tolerance to Co-Trimoxazole in HIV Positive Patient Cross Reactive to Co-Trimoxazole and Dapsone
Sukalyan Saha Roy, Nikhil Era, Shatavisa Mukherjee, Santanu Kumar Tripathi
Published: Aug. 31, 2015 | 142 148
DOI: 10.36347/sjams.2017.v05i08.049
Pages: 3228-3231
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Abstract
Co-trimoxazole and alternatively Dapsone is used for chemoprophylaxis for opportunistic infection in HIV positive patients. Desensitization to Co-trimoxazole is attempted when there is no other alternative. Different desensitization protocols are studied abroad but Indian data are much scarce. The present case reports a 28 year old newly diagnosed treatment naïve HIV positive patient who was intolerant to NACO recommended protocol but induction of tolerance was successful when dose was up-titrated at a slower rate.