DOI: 10.36347/sjams.2017.v05i08.058

Pages: 3288-3296

The incidence of chronic kidney disease and end stage renal disease are becoming significant medical problems. Cutaneous involvement can occur not only due to disease but also the predisposing factors and therapeutic dialysis. All diagnosed patients of CKD attending our institute over a one year period were included in the study. To study dermatologic manifestations in patients of chronic kidney disease including patients on renal replacement therapy. Patients with associated liver dysfunction, malignancy or pre-existing skin disorders were excluded from the study. All included patients who gave consent were examined for any dermatological involvement. The study included total of 203 patients. The most common cause of CKD in the study population was hypertension present in 71.4% of the patients followed by diabetes in 36.9%. In 93% of the patients at least one dermatological manifestation was seen with pallor being the most common (61.1%), followed by neurosis in 50.2% and hyperpigmentation in 29.5%. Sallow yellow discolouration was seen in 28.6% and pruritus in 28.1% of the patients. Purpura (14.8 %), perforating dermatosis (2%), bullous disorders 1(0.5%), follicular hyperkeratosis 10(5%), diabetic aeropathy 7(3.4%), pressure sore 3(1.5%), uremic frost 1(0.5%), delayed wound healing 2(1%) were the other dermatological involvement observed.. Pruritus was more common in patients on chronic dialysis (46.42%) than in the unanalysed subjects (24.8%). The most common nail finding was half and half nail seen in 53(26%) of patients. Nail, hair and oral mucosal changes were found in 68.47%, 19.7% and 53.2 % patients respectively. Cutaneous findings are quite common in chronic kidney disease. The understanding of the correlation between the two systems helps in managing the patient effectively.