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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-08
Relationship between Intraocular Pressure and Mean Ocular Perfusion Pressure in Hypertensive and Non Hypertensive Adult Population
Dr Bindu Thampi, Dr Antony J, Dr Mahadevan K, Dr Rekha R.S, Dr Simi F
Published: Aug. 31, 2015 | 141 145
DOI: 10.36347/sjams.2017.v05i08.062
Pages: 3313-3317
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Abstract
Aim of study was to evaluate the relationship between intraocular pressure (IOP), blood pressure (BP) and mean ocular perfusion pressure (MOPP) in patients with hypertension (HT) and compare it to a control group of normotensives. 102 hypertensive patients (HT) and 100 normotensive age matched controls were included. Best corrected visual acuity (BCVA), intraocular pressure (IOP) measurement by noncontact tonometry (NCT) and dilated fundus examination was done. Single recording of BP was taken. Visual field evaluation and gonioscopy was done for IOP >21mmHg and cup disc ratio>0.5 or asymmetry >0.2. MOPP was calculated. Duration of hypertension, details of antihypertensives, dosage and time of intake was noted. The mean IOP in right eye (RE) in HT group was 13.135 and in normotensives were 13.02. In left eye (LE) mean IOP was 13.288 in HT and 13.349 in normotensives. There was no statistically significant difference in IOP between the two groups. The MOPP was significantly higher in HT group (57.28 in RE and 57.197 in LE) than in normotensives (52.51 in RE and 52.356 in LE) with a p value<0.001.There were seven glaucoma suspects in HT group and 11 in normotensive group. There were 2 cases of ocular hypertension in HT group and 3 in normotensive group. Two subjects were diagnosed as primary open angle glaucoma (POAG) one in each group. Mean ocular perfusion pressure was significantly higher in HT group. Glaucoma suspects and Ocular HTN were significantly higher in non HTN group suggesting that decreased ocular perfusion plays a role in development of POAG.