DOI: 10.36347/sjams.2017.v05i09.025

Pages: 3598-3604

Stroke is the third leading cause of death in developed countries. Ischemic brain Injury is characterized by acute local inflammation and changes in levels of inflammatory cytokines, notably C reactive protein. High sensitivity C reactive protein can predict recurrent cardiovascular disease, stroke and death in different settings. There is lack of studies on high sensitive C reactive protein in acute ischemic stroke patients from rural area in our nation. The objective of the study was to measure high sensitivity C reactive protein levels in acute ischemic stroke and to assess short term prognosis in terms of mortality and morbidity with reference to high sensitivity C reactive protein levels during one week of hospital stay. It was a longitudinal study involving 50 patients admitted with acute ischemic stroke in medicine department. Routine investigations, high sensitivity C reactive protein levels and computed tomography scan of brain were done in all these patients. High levels of high sensitivity C reactive protein at admission showed high mortality and morbidity during one week of hospital stay. High levels of high sensitivity C reactive protein correlated with poor functional outcome using Barthel index. Thus quantitative estimation of high sensitivity C is reactive protein a simple test and helps in predicting prognosis.