DOI: 10.36347/sjams.2017.v05i09.048

Pages: 3744-3747

Nephrolithiasis is an important cause of morbidity worldwide, which has seen an increasing incidence in developing countries. By early diagnosis and treatment of these risk factors, future stone formation may be prevented. To assess the metabolic and biochemical factors associated with urinary calculi in children. Pediatric patients presenting with urolithiasis formed the sampling frame. Medical records were studied for clinical and laboratory data. Study tools were records of the patients. Metabolic evaluation was done in all children. Hundred pediatric urolithiasis cases were included in this study. Gender wise, there were 42 females (35%) and 78 males (65%) with age ranged from 1 year to 11 years (mean ± S.D., 6.40 ± 1.05 years). Big portion of stones was renal stone. Calcium oxalate stone was most common variety found in nearly 45% of the study participants. Hypocalcaemia was most common variety found in 83.33% of the study participants. Hypocalcaemia along with hyperphosphatasemia was seen in 11.67% of subjects. 56.67% (n=68) cases were managed conservatively, while remaining was managed surgically. 22.5% (n=27) had stone recurrence during follow up and 8 of these had more than one metabolic abnormality. Patients with metabolic and biochemical abnormality are more likely to have stone recurrence. Metabolic and biochemical evaluation is recommended in all pediatric patients as it helps in segregating patients needing medical therapy.