DOI: 10.36347/sjams.2017.v05i09.055

Pages: 3789-3792

The aim is to investigate the relationship between serum lipids, serum PSA and Benign Prostatic Hyperplasia (BPH) in elderly male population of Western Rajasthan. The present study was conducted on six hundred and one male subjects, 50 years or above of the age including 300 age matched controls and 301 subjects with histopathologically confirmed BPH. Patients were worked up with detailed history and clinical examination to rule out other causes of lower urinary tract symptoms (LUTS) and complications of BPH. Serum PSA and serum lipid profile was done in all patients before biopsy, digital rectal examination (DRE) or ultrasound (Abdominal/TRUS). Mean serum PSA was significantly higher in BPH subjects as compared to healthy controls. A significant correlation of serum PSA was observed with age of BPH subjects but a non-significant correlation was observed between Serum PSA and parameters of lipid profile. Mean serum total cholesterol and LDL cholesterol were significantly higher in BPH subjects as compared to healthy subjects, but a non-significant difference in serum Triglyceride, HDL and VLDL cholesterol was observed. In any elderly patient presenting with BPH, the possible presence of dyslipidemia, and other components of metabolic syndrome should be considered. Conversely in patients suffering from these conditions, the possibility of a clinically important BPH should be kept in mind.