DOI: 10.36347/sjams.2020.v08i01.047

Pages: 258-260

Cardiovascular disease according to World Health Organization (WHO, 2012) is a major cause of death worldwide (31%). The prevalence of coronary heart disease on age > 15 year old in Indonesia in 2013 is 0.5% and the prevalence in North Sulawesi based on diagnosis is 0.7% and based on symptoms 1.7%. In 2018 based on doctor diagnosis the prevalence increased to 1.8% and became a tenth rank in Indonesia. The main Lipoproteins circulated in blood are chylomicrons, Very Low Density Lipoprotein (VLDL), Low Density Lipoprotein (LDL) and High Density Lipoprotein (HDL). Intermediate Density Lipoprotein is derived from VLDL in the formation of LDL. High level of LDL will form a plaque that builds up in arteries, a condition called atherosclerosis. LDL level can be affected by several factors such as genetics, diet, weight, physical activity, smoking and alcohol consumption. Objective: The objective of this study is to determine the effect of alcohol consumption on blood LDL level. Methods: This is an observational study with a cross-sectional design on 60 male university students (Faculty of Economy and Business, University of Sam Ratulangi) aged 20 - 24 year old who consumed alcohol drink regularly. Primary and secondary data were collected using questionnaire and interview. Blood samples were analyzed in clinical laboratory with reference value of normal LDL levels <100 mg/dL: Result: Using Chi square there is significant correlation between the duration of alcohol intake and LDL levels (p<0.05), between the amount of alcohol intake and LDL levels (p<0.05) and between daily amount of alcohol intake with LDL levels. Conclusion: Alcohol consumption can influence blood LDL levels.