DOI: 10.36347/sjams.2017.v05i11.016

Pages: 4381-4396

This study was conducted to study the features of intracranial lesions of Diffusion weighted MR imaging and their correlation on other MRI sequences, to evaluate the role of DWI in etiopathogenesis and prognosis of intracranial lesions. A prospective, observational and cross section study was performed of 100 patients in 2 years period. Patient with clinical suspicion of stroke, CNS infections, head injury, demyelination and tumor were included. MRI’s were done on SIEMENS Magnetom Avanto 1.5 Tesla. Age wise distribution, complaints, intra and extra axial location of tumor, presence and absence of restricted diffusion and findings of various sequences of MRI were studied. Maximum cases were observed from 4th – 6th decades.63% of cases were observed in males while 37 of cases were seen in females.93 cases were intra-axial, 7 were extra-axial. 80% of cases showed true restriction while 20% cases showed absence of restriction. Blooming on GRE was noted in 19% of cases.56% cases of stroke comprised of arterial infarct (39%), venous infarct (3%), and white matter ischemia (9%), and acute laminar necrosis (1%), hypoxic ischemic encephalopathy, PRES (1%) and parenchyma hemorrhage (1%).15% of cases were tumor which included glioma, lymphoma, metastasis, PNET and GBM Recurrence, 5 cases of traumatic brain injury (DAI), 9 cases of epidermoid cyst (5%) and cavernous haemangioma (5%) and 6 cases of brain infection were included. MRI features of these lesions on conventional MRI sequence, DWI and ADC maps were studied. All acute and subacute arterial infarcts showed restriction on diffusion weighted images and chronic cases did not show restriction. And all three cases of venous infarcts showed restriction diffusion due to cytotoxic edema. High grade gliomas, astrocytoma’s, PNETS, lymphoma and metastasis showed diffusion restriction. Low grade gliomas did not show restriction.