DOI: 10.36347/sjams.2017.v05i11.022

Pages: 4420-4426

Breast cancer is one of the mainly common cancers in females and highly assorted disease worldwide. ICMR said in 2016 the total number of new cancer cases is likely to be about 14.5 lakh in India. Trace elements are present in small levels, but they act a vital part in plentiful biochemical enzymatic reactions and have been evaluated as a potential key constituent in various human diseases involving cancer. Natural trace elements such as: zinc, copper have some dictatorial functions that may affect immune reactions and free radical generation. The cancerous tissue directly indicates changes of trace elements that are evoked by the disease. Blood or blood constituents such as serum are considered to be the best indicators of the present exposure of an individual to many metals due to its easy sampling. In our study I was include 100 cases and 100 healthy control in which, Serum iron, copper, tumour marker CA15-3 level, Cu/Zn and Cu/Cp ratio were significantly high in breast cancer patient (p<0.001) and. Serum Zinc level is significantly decreased in breast cancer patient (p<0.001).