DOI: 10.36347/sjams.2017.v05i11.043

Pages: 4528-4533

The aim of the study was 1. To study the clinical profile of miliary Tuberculosis 2. To evaluate the treatment response by symptomatology sputum conversion, radiological resolution after 2 months and 6 months periods 3. To study the complications and incidence of MDR TB in Miliary tuberculosis. This prospective observational study was performed using a data base with 40 patients with provisional diagnosis of miliary tuberculosis during the period of Jan 2014 to April 2015. The clinico-radiological features, treatment response and incidence of complications including the incidence of MDR-TB were analyzed. In the present study mean age of study population is 41 years with male predominance (57.5%). In the present study, duration of symptoms ranged from 10 days to 3 months. Cough, fever, expectoration, loss of weight, loss of appetite, night sweats are the commonest symptoms. 2 cases are with headache and 4 cases have abdominal pain. Diabetes mellitus was seen in 5%, HIV in 12.5% cases and chronic kidney disease in 2.5% cases of study population. 97.5% cases were negative for tuberculin skin test (TST) in the study population. All cases had military mottling. Miliary mottling associated with consolidation (2 cases), pleural effusion (6cases), pleural thickening (3 case) and 3 cases had an associated cavitation. 20 cases out of 40(50%) had anemia (<10gmHb%) in the study population. Pancytopenia and leucocytosis were observed in 2.5% of the cases. In the study population 5, out of 40 (12.5%) cases were positive for sputum AFB smear. In the study population, all had miliary nodules. Four cases (10%) had associated mediastinal lymphadenopathy; one case (2.5%) had associated left multi-loculated hydro pneumothorax. One case associated with bilateral upper lobe fibrosis, 3 cases had associated cavity in upper lobe, two cases (5%) had associated segmental consolidation of both upper lobes, 6 cases (15%) had associated minimal pleural effusions (4 on right and 2 on left), 1 c