DOI: 10.36347/sjams.2017.v05i11.048

Pages: 4557-4563

Acute pancreatitis (AP) is an inflammatory process of pancreas and peripancreatic tissue, with a highly variable clinical course with high morbidity and mortality. It results from a complex etiological process, with a variable natural course, making it difficult for early identification. Most patients with AP have mild disease that resolves spontaneously, however, 10%-20% of patients experience a severe attack with high mortality of up to 30%. Early assessment and identification of patients at risk is important for initiating intensive therapy, which has shown to improve prognosis and survival. A new prognostic scoring system, the Bedside Index for Severity in Acute Pancreatitis (BISAP), is an accurate and simple method for early identification of patients at potential risk of in-hospital mortality. We aimed to assess the accuracy of BISAP score and to compare BISAP and Ranson’s scoring system in predicting the severity of acute pancreatitis. A total of 100 patients diagnosed clinically as acute Pancreatitis were included in the study. BISAP and Ranson’s scores were calculated in all patients based on data obtained within 48hours of hospitalization. Organ failure scores were calculated for all the patients during the first 72 hours of hospitalization. Duration of organ failure was graded as transient (≤ 48 hours) or persistent (>48 hours). BISAP and Ranson’s scores were analyzed statistically. All patients were managed medically and monitored for development of any complications during the hospital stay. In our study blood urea emerged as a powerful predictor of organ failure. Ranson’s and BISAP scores showed concordance on statistical analysis and BISAPs scoring system can be used to predict accurately, the severity and organ failure within hours of admission.