DOI: 10.36347/sjams.2017.v05i11.082

Pages: 4724-4729

Postmenopausal bleeding is frequent in gynaecology and accounts approximately 5-10% of postmenopausal women. The incidence of malignancy in postmenopausal period remains sufficiently high so it requires immediate investigation for early diagnosis, vigilant follow up and prompt treatment. The aims and objectives of the study is to correlate histopathology of endometrium with endometrial thickness of women with postmenopausal bleeding, to detect early pre-cancerous lesions (atypia) & endometrial hyperplasia and to confirm benign nature of problem by ruling out carcinoma, so that unnecessary surgery can be avoided. This is a non-randomized longitudinal prospective observational study done at the Department of Obstetrics & Gynaecology, Rangaraya Medical College, Kakinada during the period of December2014 –July2017. All patients having established menopause except those undergone hysterectomy/premature menopause (<40 year)/on Hormone Replacement Therapy/on anticoagulant /having bleeding disorder included. Clinical & histopathological details were collected & analyzed using mean & standard deviation. Total 50 cases were included in the study. The incidence of PMB was found to be 2.1%. Mean age of PMB was 55.96±7.70 years. Mean duration since menopause was 7.62±6.8 years. Majority (70%) were benign causes,20% had pre malignant lesion and 10% had endometrial cancer. Out of 50 women who underwent transvaginal ultrasound 26 women with postmenopausal bleeding had endometrial thickness of less than or equal to 4mm and 24 women had endometrial thickness more than 4mm.Carcinoma of genital tract is one of the most important cause of PMB, so early detection of the cause can be life saving. In the present study of 50 postmenopausal women, only one patient with endometrial thickness less than 4mm had abnormal endometrium on histopathological examination. So, Transvaginal ultrasound can be used as a screening procedure for evaluation of endometrium in postmenopausal women, taking the