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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-11
Role of CT and MR Imaging in Non Neoplastic Aetiologies of Seizure Disorder in 6-18 Yrs Age Group
Dr. Anindya Sasmal, Dr. Neelendra Chakravarty, Dr. Kausik Goswami, Dr. Tapan Dhibar, Dr. Swati Chakravarti, Dr. Gautam Ganguly, Dr. Sukanta Sen
Published: Nov. 30, 2018 | 163 137
DOI: 10.36347/sjams.2018.v06i11.013
Pages: 4221-4232
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Abstract
Neuroimaging is one of the most important advances in the past decade in the management of seizure disorder. Neuroimaging has increased substantially the ability to plan medical, surgical therapy and to prognosticate the outcome of disorder and therapy. Neuroimaging help to determine whether seizure was provoked or unprovoked. Distinction between two types of epilepsy is a major determinant in selecting the antiepileptic medicine to treat the disorder. Present study was done to identify CNS lesion in patients with seizure whether it matches with seizure semiology. And to characterize the lesion and help to plan out whether medical or surgical modalities required. It was a hospital based cross sectional observational study. Age, sex, characterization of seizure including onset, time of attack ,provocative factors, first attack, total no of attacks, frequency of attack, status of consciousness, prodrome, aura, cerebellar symptoms, duration, post ictal phenomenon, history of drug intake, control of attack by drugs, family h/o of seizure, birth history were noted. In the present study 34.5% of children belong to 6-9 yrs age group followed by 27.6% of 16-18 yrs group. Aetiologies identified through imaging process in the present study were mainly normal (24.14%), mesial temporal sclerosis, congenital structural defect and infective (17.24%) each. Causes of congenital aetiologies of seizure identified through MRI imaging was mainly Dyke Davidoff Mason syn and Arachnoid cyst (22.22% each) followed by Sturge weber syndrome, Chiari-I malformation, septo-optic dysplasia, corpus callosum agenesis, pachygyria and porencephalic cyst (11.11% each). Determining whether focal lesion is the cause of seizure also helps in diagnosis of epilepsy syndromes of childhood. Neuroimaging is useful to determine whether early intervention is required or not as in cases of traumatic seizure, vascular aetiologies of seizure.