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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-11
Evaluation of Therapeutic Effectiveness of Vitamin D in Proteinuria Regression in Diabetic Nephropathy
Dr. S.P Miital, Dr. Kiranjeet Kaur
Published: Nov. 30, 2018 | 135 194
DOI: 10.36347/sjams.2018.v06i11.022
Pages: 4275-4281
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Abstract
Albuminuria in diabetes mellitus (DM) is common and ushers the onset of systemic micro and macrovascular complications. Various metabolic and hemodynamic factors involve in the pathogenesis of albuminuria and by interacting through molecular and signaling pathways, these produce inflammatory changes and activate renin angiotensin aldosterone system (RAAS). Vitamin D has been shown to modulate both inflammation and RAAS, and hence found to be Reno protective. This study is to examine, whether vitamin D levels and albuminuria correlates inversely and how much albuminuria correction can be achieved if vitamin D is added as therapeutic adjuvant.