DOI: 10.36347/sjams.2018.v06i11.050

Pages: 4442-4446

Metabolic syndrome constitutes a cluster of risk factors characterized by hypertension, atherogenic dyslipidemia, hyperglycemia, prothrombotic and proinflammatory conditions. This cluster of metabolic abnormalities is associated with increased risk for atherosclerotic cardiovascular disease and type 2 diabetes mellitus. Thyroid hormone plays an important role on various aspects of metabolism, development and differentiation of the cells. Metabolic syndrome and thyroid dysfunction are independent risk factors for cardiovascular disease risk and mortality associated with it, it is possible that patients suffering from both these disease may have a compounded risk. The present study was a cross-sectional study design carried out at the Outpatient Department of Maheshwara Medical College & Hospital, Sangareddy, Telangana from January 2017 to August 2018. Subjects were selected and the data was collected using a structured questionnaire. A total of 154 people have given their consent for participating in the present study. Out of these, 112 were eligible after consideration of the inclusion and exclusion criteria. 100 age and sex matched subjects are selected as control group after considering the inclusion and exclusion criteria. The Ethics Committee of the Maheshwara Medical College & Hospital, Sangareddy, and Telangana has approved the study. Written informed consent in the language understandable to the subjects has been obtained from all the participants of the study. Among 100 subjects of Metabolic Syndrome and 100 subjects of control group, in our present study, there was a significant change in the levels of BMI, SBP, DBP, WC, Serum Glucose, Total Cholesterol, LDL-Cholesterol, Triglycerides, TSH, FT4 & FT3 among the Metabolic Syndrome Group when compared to Control Group. But, the levels of HDL-Cholesterol among Metabolic Syndrome and Control Group was found to be non-significant. Metabolic Syndrome is related to increased BMI, SBP, DBP, WC, Serum Glucose, Total