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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-11
Seroprevalence of IgM Antibodies to Rubella and Cytomegalovirus among Pregnant Women with bad Obstetric History Attending Tertiary Care Teaching Hospital
Dr. N. Padmapriya, Dr. P Sunitha, Dr. Rafath Fathima, Dr. P. Shashikala Reddy
Published: Nov. 30, 2018 | 160 150
DOI: 10.36347/sjams.2018.v06i11.060
Pages: 4494-4497
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Abstract
Bad obstetric history has multifactorial etiology which can be genetic, hormonal, abnormal maternal immune response, and maternal infections mainly viral infections. To study Seroprevalence of IgM antibodies to Rubella and Cytomegalovirus among pregnant women with bad obstetric history. The study design is a prospective cross-sectional study conducted among antenatal women attending the antenatal clinics with BOH from October 2017 –March 2018. Serum samples were screened for rubella and CMV specific IgM Antibody by capture ELISA. Out of 85 pregnant women, 3.5% and 12.9% pregnant women were found to be seropositive for IgM Rubella antibody and Cytomegalovirus specific IgM antibodies respectively. The predominant clinical condition responsible for BOH was abortions. Screening of pregnant women for Rubella & CMV specific IgM antibodies and timely treatment of these infections can prevent the death of infants born to infected mothers.