DOI: 10.36347/sjams.2020.v08i02.009

Pages: 404-408

Introduction: Congenital hemolytic anemia affects a significant proportion of the pediatric population globally. Numerous children are hospitalized every year due to sequelae of this heterogeneous disease. Aim of the study: The aim of this study was to focus on various aspects of presentation of congenital hemolytic anemia. Material & Methods: This was a cross sectional study conducted between January 2009 to July 2009 in the Department of Paediatrics, Rangpur Medical College Hospital, Rangpur, Bangladesh. A total number of 40 patients had been included in the study. Base line investigation was done to the new patients admitted in pediatric ward or attending at OPD of Rangpur Medical College Hospital with congenital haemolytic anemia. Case selection was done with complete blood count with peripheral blood film and haemoglobin electrophoresis. Results: In our study we found the highest number of congenital haemolytic anemic patients were with Hb-E beta thalassemia and it was 65% (n=26). Then case of Hb- E trait was 12% (n=5), case of Hb-E diseases was 10% (n=4) case of beta thalassemia major was 8% (n=3) and case of beta thalassemia minor was 5% (n=2). According to the physical examination of the participants we found, 12.50%, 35% and 7.50% patients had mild, moderate and severe progressive pallor respectively. In total 10% patients were with jaundice whereas 90% were free from that. Again 45%, 22.5% and 10% patients had splenomegaly as < 5cm, 5- 8 cm and >8 cm level. Conclusion: Nutritional and folic acid supplementation with regular blood transfusion associated with chelating therapy are essential for improving the condition of the diagnosed patients with congenital haemolytic anemia. We would like to recommend for conducting more studies with larger sized sample to get more specific information regarding congenital hemolytic anemia.