DOI: 10.36347/sjams.2018.v06i02.049

Pages: 721-723

Neo-natal sepsis is a blood infection that occurs in infants younger than 90 days old. It occurs in 1 to 8 per 1000 live birth with highest incidence occurring among infants of very low birth weight. Neo-natal sepsis is commonly associated with acute renal failure. This study aimed to determine the effect of early – onset neonatal sepsis on renal functions. This study targeted 100 Neonates affected with early onset neonatal sepsis admitted to Omdurman Pediatrics Hospital during the period of (January to July 2017). Included neonates were those affected with neonatal sepsis only and aged (1-7 days) while those affected with other diseases and aged more than 7 days, were excluded. Intravenous Blood samples were collected from all neonates affected with neonatal sepsis attending Omdurman Pediatrics’ Hospital during the period of study. Plasma was prepared for determination of renal function tests (Urea, Creatinine, Na+ and K+ and Ca++). Questionnaires were filled with mothers of affected children, to obtain information about the type and place of delivery. The findings of this study, revealed a significant increase (P≤0.05) in the level of Urea, Creatinine and Sodium, while there was no change in the level of Potassium and Calcium of affected neonates, with respect to their age, site and type of delivery, as compared to the normal reference value of the study parameters. Based on the findings of this study it can be concluded that there is a positive relationship between neonatal sepsis and the levels of Urea, Creatinine and Sodium.