DOI: 10.36347/sjams.2020.v08i02.015

Pages: 436-439

Introduction: The study was conducted to evaluate the effect of active smoking over microbiological profile of patient with symptomatic chronic rhinosinusitis (CRS) and compare the result with that of non-smokers. Methods: A cross sectional, longitudinal study, was conducted on 100 patients (15-70yr) of diagnosed chronic rhinosinusitis. Total duration of study was about one year from October 2017 to October 2018. Patients after screening were selected for study and divided in two groups, group A (n= 48, smoker) and group B (n =52, non-smokers). All subjects then underwent detail history, examination and diagnostic nasal endoscopy (DNE) and sample were collected through middle meatus swab for microbiological profile. Observation: After analyzing both group it was observed that there is significant difference in symptomatology and microbial profile in both groups. Percentage of patient presented with fever was 18%in group A vs 7% in group B. Similarly, percentage of Posterior nasal drip was 80% vs 49%, anterior nasal discharge 71%vs 29%, headache 82% vs 34% in group A and group B respectively. Percentage of KOH mount and Gram Stain positivity were significantly higher among smokers as compare with non-smokers. Proportion of aerobic bacterial isolate were higher among smoker 70% (n=28) compared with non-smokers 57.8% (n=22). Conclusion: In the study it was concluded that symptomatic presentation of CRS was more in smokers as compare with non-smokers. There is also significant higher rate of KOH mount, gram stain and aerobic culture positivity in smokers as compare to non-smokers.