DOI: 10.36347/sjams.2018.v06i03.079

Pages: 1205-1210

Dental caries being a bacterial disease accelerates the immune apparatus of the body and as a result antibodies {salivary and serum} can be found out. The major immunoglobulin in serum, is found only in low levels in salivary secretions but highest in serum where the main function Ig A is to eliminate salivary mutans or may interfere with its cariogenic activity. In contrast salivary IgA antibodies prevent streptococcus mutans from adhering to tooth surface which prevents dental caries and to activate humoral and cellular components elicited by systemic immunization. Salivary IgA levels were measured in different types of (660) Dental caries patients and compared with (140) healthy controls. It was observed that there was a significant rise in salivary IgA level and progressively higher values were obtained as the dental caries advanced the different types of dental caries studied were Initial caries, Deep caries, multiple deep caries, & Caries with pulp involvement. This study of salivary IgA may be useful in assessment and identification of severity of Dental caries.