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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-03
Study of the Effect of HAART on Lipid Profile in HIV Positive Patients
Dr. Chandraprakash, Dr. Anil Sejwar, Dr. Gopal Krishna
Published: March 30, 2018 | 144 139
DOI: 10.36347/sjams.2018.v06i03.088
Pages: 1250-1256
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Abstract
Human immunodeficiency Virus (HIV) infection is pandemic worldwide). Patients with HIV infection were reported to have hypocholesterolemia with or without hypertriglyceridemia however the mechanism of decrease in cholesterol levels is not known. Infections can increase serum triglycerides levels by decreasing clearance of circulating lipoprotein levels as process seems to inhibit the lipoprotein lipase activity or stimulating hepatic lipid synthesis through increase in either hepatic fatty acid synthesis or esterification of fatty acids derived from lipolysis. Keeping in view of the various biochemical abnormalities associated with lipid metabolism, our research was inclined to assess the lipid profile in HIV positive cases, with an attempt to further elucidate more features of HIV disease which erupts as acquired immunodeficiency syndrome (AIDS) linking any possible involvement of lipid profile in disease progression of AIDS.