DOI: 10.36347/sjams.2018.v06i03.107

Pages: 1365-1370

Urinary tract infection (UTI) is one of the most frequent types of nosocomial infections and probably affects about one-half of all people during their lifetimes. The predominant pathogen responsible for UTI is E.coli which constitutes up to 80-85% and followed by Staphylococcus saprophyticus, a Gram positive coagulase negative staphylococcus, and causes about 10% of infections among young, sexually active women. The objective of the study was to isolate Gram Positive Uropathogens causing urinary tract infections & to determine the antimicrobial susceptibility pattern of the isolates. Mid-stream urine (MSU) specimens will be collected from both inpatients (IPD) and outpatients (OPD) suspected to be having urinary tract infection. Urine microscopy will be done for pus cells and cultured on Blood agar, MacConkey agar & CLED agar. The plates will be incubated at 37◦C for 24-48 hours. Gram stain will be done to see the Gram positive cocci in pairs or short chains. During 1 year period (January 2017 to December 2017.) A total 355 urine samples of UTI suspected patients were screened 119 (33.52%) patients were showed to be urine culture positive of which 80 (67.22%) females and 39 (32.77%) Male. The isolation percentages of gram positive uropathogens were found as 45(37.81%) in which Staphylococcus aureus 22(48.88%) in which 8 were MRSA & 14 MSSA, Enterococcus spp.14 (31.11%), and Coagulase negative staph aureus (CoNS) 9(20.00%).The gram positive and gram negative bacterial proportion was 45(37.81%) and 74(62.18), respectively.The present study exhibit that staphylococcus aureus is the most common causative agent of urinary tract infection. Vancomycin, Teicoplanin and Linezolid seem to the most effective drugs for treatment of gram positive uropathogens causing UTI.