DOI: 10.36347/sjams.2023.v11i08.008

Pages: 1428-1439

Introduction: Bronchial asthma is a common heterogeneous chronic inflammatory disorder of the lower respiratory airways in childhood. Aim: This study aimed to examine different recognized risk factors of asthma. Methods: A total of 420 children sample of case-control groups of matched age (1-5 years) and gender were randomly selected and recruited in this study. The number of children in each group was (210). The cross-sectional study was conducted at Benghazi children’s hospital for six months period from 1st of June 2021 to 31st of December 2021. The data were collected using a self-administrated. The collected data were analyzed using SPSS (version 22). The chi-square test used to compare proportions. Whereas, the binary logistic regression was used to calculate the odds ratios (OR) and 95% confidence intervals (CI). Results: The result of cross-tabulation using chi-square of all different recognized factors showed a statistically significant different of p-value>0.05 were age, the family history of asthma and atopy, personal history of asthma, pet in the house, maternal medication intake, maternal treatment for the common cold, mode of delivery, preterm delivery, low birth weight, and recurrent respiratory tract infections. On other hand, the analysis of all substantial risk factors for asthma using a binary logistic regression showed age (being older (>3-5 Years)) had a protective effect against asthma (OR=0.800, (95% CI)=(0.492-1.302)), gender (being female had a protective effect against asthma (OR=0.886, (95% CI) = (0.544-1.443)), paternal (OR=0.698, (95% CI) = (0.400-1.217), not maternal educational levels had a protective against asthma, none of the personal and environmental factors affected the development of asthma in our studied children. While, the greatest contribution in this study was from natal and post natal factors including mode of delivery (OR= 0.621, (95% CI) = (0.383-1.006), and type of feeding (OR=0.854, (95% CI) = (0.515-1.416) that are a