DOI: 10.36347/sjams.2020.v08i02.029

Pages: 499-507

Introduction: Intrauterine insemination (IUI) could be the first-line option in the treatment of infertile couples with different aetiologies before moving to the more sophisticated, expensive and time-consuming techniques. Therefore, this study was conducted to evaluate prognostic factors for IUI success. Material and method: a prospective study conducted between August/2015 and January/ 2019, 188 IUI cycles were done during the study period for infertile couples attending Albayda Fertility Centre/Libya. The baseline clinical and biological characteristics were compared between the pregnant and non-pregnant groups. The pre- and post-preparation semen parameters for the husbands of both groups were also compared. Regression analyses were performed to identify the most explanatory factor for the occurrence of the clinical pregnancy after Controlled ovarian hyperstimulation (COH) and IUI. Results: the clinical pregnancy rate was 17% per cycle and 19.6% per couple. The clinical pregnancy rate was significantly and positively associated with the endometrial thickness (OR=1.4, p=0.023), and shows a significant inverse correlation with wives’age (OR=0.90, p=0.016). Conclusion: this study confirms the efficacy of IUI as an effective modality of infertility treatment. Wifes, age and endometrial thickness were the strongest predictors for IUI success.