DOI: 10.36347/sasjs.2018.v04i08.001

Pages: 138-141

The schwannoma, also called neurinoma, is a benign slow growth tumor from Schwann cells often developing at the expense of the motor and sensory peripheral nervous system. 25% of schwannomas are found in the cervicofacial sphere, but only 1% in the oral cavity; A tongue is the most affected structure. We report two cases of schwannoma of the oral cavity, the first one is in the tongue, and the second case is in the lower lip, discuss the different possible differential diagnoses, and specify the interest of the histopathological examination completed by an immunohistochemical examination, which is the only way to make the positive diagnosis of benign schwannoma. Schwannomas represent clinically a swelling along the peripheral nerves. Spontaneous pain and dysesthesia in the affected sensitive territory are common. Only surgery with histological examination and immunohistochemistry make the diagnosis possible and can differentiate schwannomas from neurofibromas and other differential diagnosis. The most commonly affected organ is the tongue. The malignant transformations of schwannomas are extremely rare. Recurrence after surgical excision is almost never observed for schwannomas. Schwannomas can also appear during the course of neurofibromatosis type I (NFI), as in NF-II. No imaging is necessary. Intraoral location of schwannoma is rare. The treatment is surgical excision. Recurrence is rarely observed.