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Scholars Journal of Medical Case Reports | Volume-11 | Issue-08
A Case of IgM Multiple Myeloma with Symptomatic Anemia and Extensive Lymphadenopathy
Imane Ait El Filali, Soukaina Haidouri, Nora El Maachi, Naoufel Benlachgar, Mouna Maamar, Hicham Harmouche, Zoubida Tazi Mezalek
Published: Aug. 29, 2023 |
95
161
DOI: 10.36347/sjmcr.2023.v11i08.031
Pages: 1554-1556
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Abstract
Immunoglobulin M multiple myeloma (IgM MM) is a rare variant of multiple myeloma (MM) accounting for less than 1% of all MM cases. In contrast, the majority of patients with MM demonstrate monoclonal IgG (52%) or IgA (21%) in their serum and urine. The clinical presentation of IgM MM can overlap with that of Waldenstrom's macroglobulinemia (WM), making it challenging to establish an accurate differential diagnosis. In this report, we present a case of IgM multiple myeloma in a patient who exhibited symptomatic anemia, extensive lymphadenopathy, and cytogenetic abnormalities commonly associated with this subtype. We provide a detailed account of the diagnostic evaluation, treatment approach, and subsequent response observed in this patient.