DOI: 10.36347/sjams.2018.v06i04.008

Pages: 1416-1421

In urban Indian population due to various emerging etiological factors such as stress and unhealthy lifestyle, risk of getting coronary artery disease (CAD) in young patients is increasing. Platelets play an important role in pathogenesis of atherosclerosis. Larger platelets are hemodynamically active; they are etiological agents forming thrombosis in arteries. The present study deals with the correlation of platelet volume indices (PVI) in patients with CAD and healthy controls. We observed that, cases were almost equally distributed in 3rd to 5th decade of life. Males outnumbered females. Values of PVI – Mean Platelet Volume (MPV) and Platelet Large Cell Ratio (P-LCR) were highly significant in patients with coronary artery disease compared to healthy controls. Cut off obtained for mean MPV 9.4fL and P-LCR 40 %. PVI are simple, effortless and cost effective tool, generated as a byproduct of hematoanalyzers, can be used in predicting development of CAD sometime in near future.