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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-04
Lipid Profiles in Atherosclerosis
Dr. Deepti Agnihotri, Dr. Shreya Nigoskar, Dr. Kapil Shrivastava
Published: April 30, 2018 | 132 152
DOI: 10.36347/sjams.2018.v06i04.022
Pages: 1496-1499
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Abstract
A study on lipoprotein oxidation and its significance for atherosclerosis: a mathematical approach. Atherosclerosis is a chronic disease which involves the buildup of cholesterol and fatty deposits within the arterial wall. This results in the narrowing of the vessel lumen, which eventually restricts blood flow to vital organs such as the heart and lungs. These events may culminate in a heart attack or stroke, the commonest causes of atherosclerosis which include the buildup of cholesterol within sub endothelial cells to form what is known as a fatty streak, the earliest identifiable evidence of atherosclerosis. Study on lipid profile levels on the second day of acute myocardial infarction; is it the right time for estimation? The main objective of this study is to note the changes that occur in the lipid profile levels following an acute myocardial ischemic attack. The lipid parameters like High density lipoprotein (HDL) had shown significant decrease and the Very low density lipoprotein (VLDL) and triglycerides (TG) had shown significant increases in cases compared to normal healthy individuals. Total cholesterol (TC) and low density lipoprotein (LDL) in cases had shown decreases compare to controls but not significant statistically. The cTnI showed a significant negative correlation with decreases in the TC and HDL and LDL. The AST showed significant negative correlation with TC and LDL only. So routine diagnosis of lipid parameter for assessing the clinical risk should be reliably assessed within 24 hours and the lipid parameters assessed after 24 hours are invalid for risk assessment for patients with AMI. Study on Atherosclerosis –an inflammatory disease. They said that atherosclerosis is an inflammatory disease. Because high plasma concentration of cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the principal those risk factors for atherosclerosis, the process of thermogenesis has been considered by many to consist la