DOI: 10.36347/sjams.2018.v06i04.045

Pages: 1598-1602

Preeclampsia is a common medical complication of pregnancy. It is one of the leading cause of maternal and foetal morbidity and mortality. Several studies have demonstrated the relationship between platelet indices and preeclampsia with variable results. To evaluate the relationship between platelet count and platelet indices and their significance in preeclampsia. To study the platelet count and indices in preeclampsia and compare to normal pregnant women and to study their role in diagnosis of severity of preeclampsia. This study was a prospective case control study done over a period of two years in a tertiary care Hospital and Research centre, Pune. Study comprised of 200 pregnant women of which 100 were normotensive and 100 had preeclampsia (mild to moderate grade:89, severe grade:11). Blood samples were analysed for platelet count and indices in both groups and results were compared. Platelet count decreased and platelet indices like Mean Platelet Volume (MPV), Platelet Distribution Width (PDW), Platelet Large Cell Ratio (P-LCR) were significantly increased in preeclampsia as compared to normotensive women. Platelet count decreased and platelet indices increased in severe grade of preeclampsia as compared to mild-moderate grade however there was no statistical significant difference. Platelet count and indices can be used for early detection of preeclampsia. Rise in platelet indices suggests increased severity of preeclampsia which alerts physician for close management of the patient.