DOI: 10.36347/sjams.2018.v06i04.049

Pages: 1616-1622

Bloodstream infections (BSIs) are one of the common causes of infective morbidity and mortality. Early detection of causative pathogens and their antimicrobial resistance helps to start the appropriate antimicrobial therapy thereby reducing the number of complications. The present study was conducted to determine the bacteriological profile of bloodstream infections and their antibiotic resistance pattern in our tertiary care setup. Blood samples were received in the department of Microbiology, Hind institute of medical sciences, Barabanki. The sample processing and identification was done as per the standard protocol. Antibiotic sensitivity testing was done using Kirby Bauer disk diffusion method as per Clinical Laboratory Standard Institute (CLSI) guidelines. A total of 521 samples were processed, out of which 174(33.4%) isolates were positive for bacterial growth. From 174 bacterial culture positive isolates, 62% gram positive and 38% gram negative bacteria were isolated respectively. The most common bacteria isolated was Coagulase negative Staphylococcus spp (CoNS) (33%) followed by Staphylococcus aureus(25%), Escherichia coli(10%) and Acinetobacter spp. (10%). All gram positive cocci were completely sensitive to linezolid and teichoplanin. The present study observed high prevalence of antimicrobial resistance both in gram positive and gram negative bacteria. Hence, it is important to know the current trend of antimicrobials and formulate the antibiotic policy in the hospital so that the clinicians can start the proper empirical treatment and prevent the injudicious use of antibiotics.