DOI: 10.36347/sjams.2018.v06i04.094

Pages: 1838-1841

Despite its functional nature, hepatorenal syndrome (HRS) is associated with a poor prognosis and the only effective treatment is liver transplantation. It is very important to diagnose renal impairment in cirrhosis patients at an early stage before overt HRS develops. To study and compare demographic, clinical, biochemical parameters between different complications of liver cirrhosis with special reference to HRS. Hundred liver cirrhosis patients were studied in J.A. Group of Hospitals, Gwalior from November 2014 to September 2016. Detailed history, chief complaints, history of present and past illness, personal history, occupational history, family history, drug and addiction history was taken. General and systemic examination of patients was done. All routine investigation like renal function test, liver function test, urine R/M, USG abdomen, renal color doppler, was performed after dividing patients into Group A (patients with compensated liver cirrhosis), Group B (patients with decompensated cirrhosis responsive to diuretics), Group C (patients with decompensated cirrhosis resistant to diuretics) and Group D (patients with hepatorenal syndrome). Male preponderance (84%) was observed with mean age of 45.34±13.98 years. Most of the patients had decompensated cirrhosis (n=97). Most common cause of liver cirrhosis was alcohol (n=68). Blood urea (n=12) and serum creatinine (n=13) was higher in patients with HRS. Hepatic Encephalopathy was more common in HRS patients (n=8). Out of 11 patients with spontaneous bacterial peritonitis (SBP), 27.27% patient found to have hepatorenal syndrome. HRS is common among male patients who consume alcohol. Blood urea and serum creatinine were increased. Hepatic Encephalopathy and SBP were common fining in HRS in liver cirrhosis patients.