DOI: 10.36347/sjams.2020.v08i03.028

Pages: 939-944

Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory disabling disease. It is a spectrum of airway disease characterized by the chronic bronchitis (airway obstruction) & emphysema (parenchymal destruction).The major cause for morbidity & mortality in worldwide is COPD &it is the fourth leading cause of death in world. Objective of the Study: To identify the most common bacterial organism isolated from sputum of COPD patients from Out Patient in National Institute of Diseases of the Chest & Hospital (NIDCH). Material & Methods: Patients who were >40 years old attended Medical OPD at National Institute of Diseases of the Chest & Hospital (NIDCH), Mohakhali, Dhaka, Bangladesh from January 2018 to December 2018, diagnosed with COPD and having symptoms of acute exacerbation were screened for participation. Samples were collected in sterile vial & sent within 2 hours to the central laboratory. Sputum sample to be deemed acceptable for analysis; Microbiological study done by using a low magnification lens (x100) reveals <10 epithelial cells & >25 leucocytes per field. Selected sputa were processed microbiologically for quantitative study following accepted laboratory method. Results: Total of 70 patients, fulfilling the inclusion & exclusion criteria, 40 male & 30 female with 57% & 43%. Out of 70 patients, 19 showed the overgrowth of the normal commensal in sputum, so only 51 patients (72%) showed growth with culture positive. In terms of age, the study group belongs to a wide range from 40 years to > 80 years with maximum patients (35%) belonging to the age group of 50 -60 years followed by 60-70 years (25%) and 40-50 years (21.88%), Streptococcus pneumonia (14 cases, 27%), Hemophilus influenza(10 cases, 20%), Pseudomonas aeruginosa (7 cases, 14%), Moraxella catarrhalis (6 cases, 12%), Eschericia coli (4 cases, 8%), Staphlococcus aureus (3 cases, 6%), Citrobacter freundii (3 cases, 6%), Klebsiella pneumonia (2 cases, 4%), Acinetobacter.....