DOI: 10.36347/sjams.2018.v06i05.018

Pages: 1964-1967

The aim of the study is to compare Isosorbide Mononitrate and Dinoprostone gel for cervical ripening in terms of efficacy and safety. In this study 220 pregnant women attending the antenatal clinics were evaluated and were selected for the study after applying inclusion and exclusion criteria and divided in 2 groups with 110 patients in each group. In group A 40 mg Isosorbide Mononitrate (IMN) was used for cervical ripening whereas in group B Dinoprostone gel (PGE2) was used. Both the groups were compared in term of efficacy and safety. In our study significant change in Bishop’s score, fewer requirements of oxytocin, and short induction delivery interval was found in PGE2 group as compared to IMN group, whereas adverse effects like Tachysystole, Hyperstimulation and admission to NICU were less in IMN group. IMN is cheaper and effective alternative to dinoprostone for cervical ripening and induction of labour at term despite its shortcomings and those women who do not respond to IMN must be given a trial with intracervical PGE2 gel for which further studies are required.