DOI: 10.36347/sjams.2018.v06i05.025

Pages: 1991-1995

Diabetes Mellitus is a metabolic disorders and one of the leading cause of morbidity and mortality. A prospective randomized open parallel group study was conducted in 180 patients of either sex in the age group 40-60 years in medicine department of Muzaffarnagar Medical College. Total 180 patients were divided into 3 groups. Group-1(n=60) was taken as control while group-2(n=60) and group-3(n=60) was taken as test groups and were given Barberis Arista. Group 2 patients received 1.5 gm and group 3 patients received 3 gm of Barberis Arista respectively as an add on therapy along with the standard oral anti-diabetic treatment. In the study there was improvement and stabilization of glycemic control in test group-2 and 3 when compared with control group (p < 0.01). In group-2 and 3 there was reduction in Fasting blood sugar level after 1 month , while post prandial blood sugar[PPBS] level in group 2 was significantly reduced after 2nd month(p<0.01), but in group -3 there was no significant reduction in PPBS level upto 8th month. Afterwards a significant reduction was seen (p<0.01). There was highly significant reduction of HbA1c 3rd month onwards in both test groups (p<0.001) So it can be concluded that Berberis Aristata as an add on therapy in type 2 DM patients has a beneficial role with regard to the hyperglycemia.