DOI: 10.36347/sjams.2018.v06i06.011

Pages: 2363-2372

Chronic kidney disease leads to many co morbidities that affects patients at all stages of the disease. Complications are due to disease itself as well as the mode of renal replacement therapy. Cardiovascular morbidity and mortality is highest in the dialysis population. Recently there has been found an association between Renal replacement therapy and development of pulmonary hypertension. The main objective is to study the prevalence of pulmonary hypertension among non-dialysis and dialysis dependent chronic kidney disease patients. A total of 100 CKD patients, with 50 each in the non-dialysis and dialysis groups were included. The parameters like, etiology for CKD, hemoglobin levels, duration of dialysis, 2D Echocardiogram for the presence and severity of pulmonary hypertension among the patients in non-dialysis and dialysis dependent groups was studied. Among the 100 CKD patients, 44(44%) had pulmonary hypertension (PH) and in these 44 patients, 40(90.9%) patients were on dialysis which is significant with linear relation between duration of dialysis and severity of PH. The mechanisms underlying development of pulmonary hypertension in CKD patients are more complex. This unrecognized complication of maintenance hemodialysis therapy is associated with reduced survival. Detection of Pulmonary Hypertension in CKD patients may also help in prognosis in the post-transplantation period.