DOI: 10.36347/sjams.2018.v06i06.025

Pages: 2436-2439

Breast cancer is the most common cancer in women worldwide. In this study 43 patients were included into this part prospective and part retrospective study. Ki 67 assessment was done on tumor tissue and lymph node involvement was determined by histopathological analysis. The association between lymph node positivity and Ki67was analyzed. Lymph node involvement was found in 24 patients .Mean Ki-67 score for lymph node negative and positive cases of breast carcinoma was 11.89 and 17.54 respectively. T-test applied and the relation between tem found is statistically significant with p- value 0.044. The high levels of Ki-67 were positively correlated with a higher incidence of lymph node metastasis. Our data suggest that Ki-67 positivity has value as a prognostic and predictive biomarker in breast cancer and may be a valuable proliferation marker in routine diagnosis of breast cancer